Dr. Maura Isles has barely had time to recover from the startling revelations about her family in ody Double (2004) when she discovers one of the corpses in her morgue is very much alive. The young woman is rushed off to the hospital, where the doctors are able to save her life. Maura pays the young woman a visit only to witness the woman grab a security guard's gun, shoot the man, and take Maura hostage. Maura manages to escape, and the woman flees into the bowels of the hospital, where she takes six other people hostage, including Detective Jane Rizzoli, who is about to give birth. The woman refuses to communicate with the police, but she manages to get a signal out through a local radio station to a man who slips past the police barricade to join her in the hospital. Jane's husband, FBI agent Gabriel Dean, becomes very suspicious when the situation attracts the attention of the highest levels of government. Hoping to save his wife, Gabriel begins his own investigation and is startled when he uncovers a shocking conspiracy.